Bayani:A cikin shekara ta 2035, mai laifin James Cole ya ba da agajin gaggawa don a dawo da shi cikin lokaci don gano asalin wata cuta mai kisa wacce ta shafe kusan dukkanin al'ummar duniya tare da tilasta wa wadanda suka tsira zuwa cikin al'ummomin karkashin kasa. Amma lokacin da aka aika Cole cikin kuskure zuwa 1990 maimakon 1996, an kama shi kuma an kulle shi a asibitin kwakwalwa. A can ya sadu da likitan hauka Dokta Kathryn Railly, da kuma mai haƙuri Jeffrey Goines, ɗan sanannen ƙwararren ƙwararrun ƙwayoyin cuta, wanda zai iya riƙe maɓalli ga ƙungiyar 'yan damfara mai ban mamaki, Sojojin Birai 12, waɗanda ake tunanin ke da alhakin ƙaddamar da cutar ta kisa.